La eficacia de la Sputnik V contra el coronavirus es superior al 95%, según otro análisis preliminar

La eficacia de la vacuna Sputnik V es superior al 95% a los 21 días de la segunda dosis, anunciaron hoy el Centro Gamaleya de Rusia y el Fondo de Inversión Directa de Rusia (RDIF), en base a un segundo análisis intermedio del ensayo clínico de fase 3, en tanto que confirmaron que su valor será de menos de 10 dólares por dosis.

La evaluación de la eficacia se llevó a cabo entre 18.794 voluntarios 28 días después de recibir la primera dosis (7 días después de la segunda dosis) de la vacuna o placebo sobre la base de 39 casos confirmados de coronavirus, de los cuales 31 se dieron en quienes habían recibido placebo y 8 en los inoculados con la vacuna.

Como la relación entre el grupo placebo y el grupo vacunado es de 1 a 3, sobre esa cantidad de casos, la Sputnik V demuestra una eficacia del 91,4% siete días después de la segunda dosis.

No obstante, “los datos preliminares sobre los voluntarios en el día 42 después de la primera dosis (equivalente a 21 días después de la segunda dosis), cuando ya han formado una respuesta inmune estable, indican que la tasa de eficacia de la vacuna está por encima del 95%”, informó el Centro Gamaleya en el comunicado.

“Esta eficacia es el resultado del uso de dos adenovirus diferentes que se administra cada uno en una de las dosis, lo que aumenta la respuesta inmune“, explicó esta mañana en una conferencia de prensa con medios internacionales Denis Logunov, vicedirector del Gamaleya y quien está a cargo del equipo de desarrollo de la vacuna.

En este sentido, añadió que “este análisis preliminar es el segundo que hacemos en base al protocolo que se había establecido, el siguiente será cuando se lleguen a los 78 casos de coronavirus; no obstante estimamos que el porcentaje de eficacia no bajará ni subirá demasiado”.

Durante la conferencia virtual, de la que participó Télam, Logunov señaló que “durante este tiempo no registramos efectos adversos graves, sí tuvimos algunos efectos como febrícula o dolor en el lugar de la inyección en un 30 y un 40% de los participantes”.

Por su parte, Kirill Dmitriev, director general del Fondo Ruso de Inversión Directa (RDIF) -también presente en la conferencia-, confirmó que “el precio de la vacuna será inferior a 10 dólares por dosis, lo que implica menos de 20 dólares por esquema, una cifra que es casi la mitad de los precios anunciados por las otras vacunas que tuvieron indicadores similares en sus resultados preliminares de fase 3”.

Dmitriev ratificó, además, la elaboración de la vacuna en forma liofilizada (seca), que permite su almacenamiento a una temperatura de +2 a +8 grados Celsius, lo que facilita la distribución.

“A diferencia de otras vacunas que necesitan condiciones como el ultrafrío para conservarse, la nuestra estará disponible en forma seca lo que será de gran utilidad para muchos países”, describió.

Con respecto al momento en que llegarían las vacunas a los países que la solicitaron, Dmitriev detalló que “las dosis estarán disponibles en enero con los países con los que ya venimos cerrando los acuerdos y en marzo para el resto”.

La vacuna rusa es una sobre las que están avanzadas las conversaciones del Gobierno argentino para su adquisición, al tiempo que también fue sellado ya un acuerdo con la farmacéutica AstraZeneca, y mantiene negociaciones negociaciones con Pfizer, Janssen y Sinopharm.

Hasta el 24 de noviembre, más de 22.000 voluntarios fueron vacunados con la primera dosis y más de 1.900 voluntarios con la primera y la segunda dosis de la vacuna en 29 centros médicos en Rusia como parte de los ensayos clínicos en curso que aspiran a llegar a 20 mil participantes.

Actualmente, los ensayos clínicos de fase III están aprobados y están en curso en Bielorrusia, los Emiratos Árabes Unidos, Venezuela y otros países, así como la fase II-III en la India.

La Sputnik V es una vacuna que utiliza una tecnología que se llama “vector viral no replicante”; los vectores son virus que no tienen capacidad de reproducirse en el organismo (y por tanto son inocuos) y se utilizan para transportar material genético del virus del que se quiere inmunizar.

A diferencia de otras que utilizan esta tecnología, esta vacuna es la única que utiliza dos adenovirus (virus que causan gripe común) humanos como vectores, uno diferente en cada dosis que se dan intramuscularmente con diferencia de 21 días.




About The Author

65 thoughts on “La eficacia de la Sputnik V contra el coronavirus es superior al 95%, según otro análisis preliminar

  1. I have observed that in digital camera models, special receptors help to {focus|concentrate|maintain focus|target|a**** automatically. The sensors involving some camcorders change in contrast, while others make use of a beam involving infra-red (IR) light, particularly in low lighting. Higher spec cameras oftentimes use a combination of both methods and might have Face Priority AF where the photographic camera can ‘See’ your face and focus only in that. Thank you for sharing your thinking on this web site.

  2. According to my study, after a foreclosures home is offered at a bidding, it is common for the borrower in order to still have any remaining unpaid debt on the loan. There are many loan providers who seek to have all service fees and liens paid by the up coming buyer. Nevertheless, depending on specified programs, regulations, and state legislation there may be a number of loans that aren’t easily resolved through the shift of lending products. Therefore, the responsibility still lies on the client that has acquired his or her property in foreclosure. Thank you sharing your thinking on this site.

  3. Hi there, i read your blog occasionally and i own a
    similar one and i was just wondering if you get a lot of spam responses?

    If so how do you stop it, any plugin or anything you can advise?
    I get so much lately it’s driving me insane so any help is very much appreciated.

  4. I think this is among the most important information for me.
    And i’m glad reading your article. But wanna remark on some general things,
    The website style is wonderful, the articles is
    really excellent : D. Good job, cheers

  5. After I originally left a comment I appear to have clicked on the -Notify me when new comments are added- checkbox and now whenever a comment is added I recieve four emails with the exact same comment. There has to be an easy method you can remove me from that service? Thanks a lot!

  6. hey there and thank you for your info – I’ve definitely picked up
    something new from right here. I did however expertise some technical issues using this
    website, since I experienced to reload the site lots of times previous to I
    could get it to load correctly. I had been wondering if your web
    host is OK? Not that I am complaining, but slow loading
    instances times will sometimes affect your placement in google
    and could damage your quality score if ads and marketing
    with Adwords. Well I’m adding this RSS to my email and could look out for a lot more of your respective
    intriguing content. Make sure you update this again soon.

  7. Nice post. I was checking constantly this blog and I am impressed!
    Extremely useful information specifically the last part :
    ) I care for such information a lot. I was seeking this particular information for a long time.
    Thank you and best of luck.

  8. Oh my goodness! Amazing article dude! Many thanks, However I am having difficulties with your RSS. I don’t understand the reason why I cannot subscribe to it. Is there anyone else having identical RSS problems? Anyone that knows the solution will you kindly respond? Thanks!!

  9. Hi, I do believe this is an excellent blog. I stumbledupon it 😉 I will
    return once again since i have book marked it.

    Money and freedom is the greatest way to change, may you be rich and
    continue to help other people.

  10. You really make it appear really easy together with your
    presentation but I find this matter to be actually something that
    I believe I would by no means understand. It seems too complex and very huge for me.
    I am looking forward on your next submit, I will attempt to get the grasp
    of it!

  11. If you would like to increase your know-how just keep visiting this web site
    and be updated with the most up-to-date news update posted

  12. Everything is very open with a really clear description of the challenges.
    It was definitely informative. Your website is very
    helpful. Thanks for sharing!

  13. I am extremely impressed with your writing skills as well as with the layout on your weblog.
    Is this a paid theme or did you modify it yourself?
    Anyway keep up the nice quality writing, it’s rare to see a great
    blog like this one nowadays.

  14. You could definitely see your skills within the work you write.
    The world hopes for even more passionate writers such as you who are not afraid to say how they
    believe. Always follow your heart.

  15. I’m not sure where you’re getting your information, but good topic.
    I needs to spend some time learning more or understanding more.
    Thanks for great info I was looking for this information for my mission.

  16. I’ve been browsing online more than 4 hours today,
    yet I never found any interesting article like
    yours. It is pretty worth enough for me. In my opinion, if all webmasters and bloggers made good content as you did, the net will be a lot more useful than ever before.

  17. I am really enjoying the theme/design of your web site.
    Do you ever run into any web browser compatibility issues?

    A couple of my blog visitors have complained about my website not operating
    correctly in Explorer but looks great in Opera. Do you have
    any solutions to help fix this problem?

  18. Just want to say your article is as amazing. The
    clarity in your post is simply excellent and i could assume you’re an expert on this subject.
    Fine with your permission allow me to grab your RSS feed to keep up to date with forthcoming post.
    Thanks a million and please keep up the enjoyable work.

  19. Hello there, You have done an excellent job. I will certainly digg it and personally suggest to my friends.
    I am confident they’ll be benefited from this
    web site.

  20. Nice blog here! Additionally your site quite
    a bit up very fast! What web host are you the usage of?
    Can I am getting your affiliate hyperlink for your host?
    I want my web site loaded up as quickly as yours lol

  21. I am extremely impressed with your writing
    skills and also with the layout on your weblog. Is this a paid theme or did you modify it
    yourself? Anyway keep up the excellent quality writing, it’s rare to see
    a great blog like this one these days.

  22. Good day! I could have sworn I’ve been to this website before but after going through a few of the articles
    I realized it’s new to me. Anyhow, I’m definitely happy I came across it
    and I’ll be bookmarking it and checking back frequently!

  23. It’s genuinely very complicated in this full of activity life to listen news on TV, therefore I simply
    use world wide web for that purpose, and get the most recent information.

  24. I like the valuable information you provide in your articles.
    I’ll bookmark your blog and check again here frequently.
    I’m quite certain I will learn plenty of new stuff right here!
    Good luck for the next!

  25. We would like to thank you all over again for the gorgeous ideas you offered Janet when preparing a post-graduate research
    in addition to, most importantly, with regard to providing
    every one of the ideas in one blog post. Provided
    that we had known of your site a year ago, we might have been kept from the
    nonessential measures we were choosing. Thanks to you.
    toys for adults

Deja un comentario

Tu dirección de correo electrónico no será publicada. Los campos obligatorios están marcados con *